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Marker exchange mutagenesis of the aerolysin determinant in Aeromonas hydrophila demonstrates the role of aerolysin in A. hydrophila-associated systemic infections.

We report here on the isolation of isogenic strains of Aeromonas hydrophila AB3 deleted for a segment of the aerolysin gene. All aer mutants obtained lacked the 49-kilodalton aerolysin gene product and were neither hemolytic for blood erythrocytes nor cytotoxic for Chinese hamster ovary tissue cultu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Chakraborty, T, Huhle, B, Hof, H, Bergbauer, H, Goebel, W
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3305370/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.9.2274-2280.1987
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