Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity

OBJECTIVE—Osteopontin (OPN) plays an important role in the development of insulin resistance and liver complications in dietary murine models. We aimed to determine the expression pattern of OPN and its receptor CD44 in obese patients and mice according to insulin resistance and liver steatosis. RES...

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Detalhes bibliográficos
Main Authors: Bertola, Adeline, Deveaux, Vanessa, Bonnafous, Stéphanie, Rousseau, Déborah, Anty, Rodolphe, Wakkach, Abdelilah, Dahman, Moncef, Tordjman, Joan, Clément, Karine, McQuaid, Siobhán E., Frayn, Keith N., Huet, Pierre-Michel, Gugenheim, Jean, Lotersztajn, Sophie, Le Marchand-Brustel, Yannick, Tran, Albert, Gual, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606860/
https://ncbi.nlm.nih.gov/pubmed/18952835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0400
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