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Sirolimus Reduces the Incidence and Progression of UVB-Induced Skin Cancer in SKH Mice even with Co-administration of Cyclosporine A

Transplant immunosuppressants have been implicated in the increased incidence of non-melanoma skin cancer in transplant recipients, most of whom harbor considerable UVB-induced DNA damage in their skin prior to transplantation. This study was designed to evaluate the effects of two commonly used imm...

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Detalhes bibliográficos
Main Authors: Wulff, Brian C., Kusewitt, Donna F., VanBuskirk, Anne M., Thomas-Ahner, Jennifer M., Jason, Duncan F., Oberyszyn, Tatiana M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606089/
https://ncbi.nlm.nih.gov/pubmed/18463679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.121
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