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Aging Impairs Recipient T Cell Intrinsic and Extrinsic Factors in Response to Transplantation

BACKGROUND: As increasing numbers of older people are listed for solid organ transplantation, there is an urgent need to better understand how aging modifies alloimmune responses. Here, we investigated whether aging impairs the ability of donor dendritic cells or recipient immunity to prime alloimmu...

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Detalhes bibliográficos
Main Authors: Shen, Hua, Tesar, Bethany M., Du, Wei, Goldstein, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606020/
https://ncbi.nlm.nih.gov/pubmed/19119314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004097
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