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Aging Impairs Recipient T Cell Intrinsic and Extrinsic Factors in Response to Transplantation

BACKGROUND: As increasing numbers of older people are listed for solid organ transplantation, there is an urgent need to better understand how aging modifies alloimmune responses. Here, we investigated whether aging impairs the ability of donor dendritic cells or recipient immunity to prime alloimmu...

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Autori principali: Shen, Hua, Tesar, Bethany M., Du, Wei, Goldstein, Daniel R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606020/
https://ncbi.nlm.nih.gov/pubmed/19119314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004097
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