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Facilitated Recycling Protects Human RNA Polymerase III from Repression by Maf1 in Vitro

Yeast cells synthesize ∼3–6 million molecules of tRNA every cell cycle at a rate of ∼2–4 transcripts/gene/s. This high rate of transcription is achieved through many rounds of reinitiation by RNA polymerase (pol) III on stable DNA-bound complexes of the initiation factor TFIIIB. Studies in yeast hav...

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Detalhes bibliográficos
Main Authors: Čabart, Pavel, Lee, JaeHoon, Willis, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606008/
https://ncbi.nlm.nih.gov/pubmed/18974046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807538200
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