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Distinct Roles of Heterogeneous Nuclear Ribonuclear Protein K and microRNA-16 in Cyclooxygenase-2 RNA Stability Induced by S100b, a Ligand of the Receptor for Advanced Glycation End Products

Advanced glycation end products play major roles in diabetic complications. They act via their receptor RAGE to induce inflammatory genes such as cyclooxygenase-2 (COX-2). We examined the molecular mechanisms by which the RAGE ligand, S100b, induces COX-2 in monocytes. S100b significantly increased...

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Detalhes bibliográficos
Main Authors: Shanmugam, Narkunaraja, Reddy, Marpadga A., Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606002/
https://ncbi.nlm.nih.gov/pubmed/18854308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806322200
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