Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure

Haploinsufficiency of the transcription factor TWIST1 is associated with Saethre-Chotzen Syndrome and is manifested by craniosynostosis, which is the premature closure of the calvaria sutures. Previously, we found that Twist1 forms functional homodimers and heterodimers that have opposing activities...

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Bibliografiske detaljer
Main Authors: Connerney, Jeannette, Andreeva, Viktoria, Leshem, Yael, Mercado, Miguel A., Dowell, Karen, Yang, Xuehei, Lindner, Volkhard, Friesel, Robert E., Spicer, Douglas B.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605972/
https://ncbi.nlm.nih.gov/pubmed/18471809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.03.037
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