Protein kinase C beta (PKCβ) in malignant pleural mesothelioma

PURPOSE: Malignant pleural mesothelioma (MPM) is a disease with few therapeutic options. Protein kinase C beta (PKCß) is involved in important cellular functions. Enzastaurin (LY317615.HCl) is a novel inhibitor of PKC in clinical development. EXPERIMENTAL DESIGN: MPM cell lines (7) and patient tumor...

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Autores principales: Faoro, Leonardo, Loganathan, Sivakumar, Westerhoff, Maria, Modi, Rahul, Husain, Aliya N., Tretiakova, Maria, Seiwert, Tanguy, Kindler, Hedy L., Vokes, Everett E., Salgia, Ravi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605682/
https://ncbi.nlm.nih.gov/pubmed/18765998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e32830ce506
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