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Mutations in the SOD2 Promoter Reveal a Molecular Basis for an AP-2-Dependent Dysregulation of MnSOD Expression in Cancer Cells
A primary antioxidant enzyme in mitochondria, Manganese superoxide dismutase (MnSOD) plays a critical role in the survival of aerobic life. It is well-documented that compared to normal cell counterparts, MnSOD level is decreased in neoplastic transformed cells but is increased in aggressive cancers...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605667/ https://ncbi.nlm.nih.gov/pubmed/19074833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0253 |
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