Elevation of circulating big endothelin-1: an independent prognostic factor for tumor recurrence and survival in patients with esophageal squamous cell carcinoma

BACKGROUND: Endothelin(ET) axis plays a key role in many tumor progression and metastasis via various mechanisms such as angiogenesis, mediating extracellular matrix degradation and inhibition of apoptosis. However, there is limited information regarding the clinical significance of plasma big ET-1...

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Hauptverfasser: Jiao, Wenjie, Xu, Jing, Zheng, Jinsheng, Shen, Yi, Lin, Lesheng, Li, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605466/
https://ncbi.nlm.nih.gov/pubmed/19014602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-334
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