Herpes Simplex Virus Type 1 Us3 Gene Deletion Influences Toll-like Receptor Responses in Cultured Monocytic Cells

BACKGROUND: Toll-like receptors have a key role in innate immune response to microbial infection. The toll-like receptor (TLR) family consists of ten identified human TLRs, of which TLR2 and TLR9 have been shown to initiate innate responses to herpes simplex virus type 1 (HSV-1) and TLR3 has been sh...

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Main Authors: Peri, Piritta, Mattila, Riikka K, Kantola, Helena, Broberg, Eeva, Karttunen, Heidi S, Waris, Matti, Vuorinen, Tytti, Hukkanen, Veijo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605447/
https://ncbi.nlm.nih.gov/pubmed/19025601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-140
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