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Transient antiretroviral therapy selecting for common HIV-1 mutations substantially accelerates the appearance of rare mutations

BACKGROUND: Highly selective antiretroviral (ARV) regimens such as single dose nevirapine (NVP) used for prevention of mother to child transmission (PMTCT) in resource-limited settings produce transient increases in otherwise marginal subpopulations of cells infected by mutant genomes. The longer te...

詳細記述

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書誌詳細
主要な著者: Shiri, Tinevimbo, Welte, Alex
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605440/
https://ncbi.nlm.nih.gov/pubmed/19014593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-5-25
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