Intravenous Administration of Glial Cell Line-Derived Neurotrophic Factor Gene-Modified Human Mesenchymal Stem Cells Protects Against Injury in a Cerebral Ischemia Model in the Adult Rat

Intravenous administration of human mesenchymal stem cells (hMSCs) prepared from adult bone marrow has been reported to ameliorate functional deficits after cerebral artery occlusion in rats. Several hypotheses to account for these therapeutic effects have been suggested, and current thinking is tha...

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Bibliographic Details
Main Authors: Horita, Yoshifumi, Honmou, Osamu, Harada, Kuniaki, Houkin, Kiyohiro, Hamada, Hirofumi, Kocsis, Jeffery D.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605367/
https://ncbi.nlm.nih.gov/pubmed/16998918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21056
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