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Deletion of Trpm7 Disrupts Embryonic Development and Thymopoiesis Without Altering Mg(2+) Homeostasis
The gene transient receptor potential-melastatin-like 7 (Trpm7) encodes a protein that functions as an ion channel and a kinase. TRPM7 has been proposed to be required for cellular Mg(2+) homeostasis in vertebrates. Deletion of mouse Trpm7 revealed that it is essential for embryonic development. Tis...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605283/ https://ncbi.nlm.nih.gov/pubmed/18974357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163493 |
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