Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

Autoantibodies against double-stranded DNA (dsDNA) and nucleosomes represent a hallmark of systemic lupus erythematosus (SLE). However, the mechanisms involved in breaking the immunological tolerance against these poorly immunogenic nuclear components are not fully understood. Impaired phagocytosis...

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Detalhes bibliográficos
Main Authors: Urbonaviciute, Vilma, Fürnrohr, Barbara G., Meister, Silke, Munoz, Luis, Heyder, Petra, De Marchis, Francesco, Bianchi, Marco E., Kirschning, Carsten, Wagner, Hermann, Manfredi, Angelo A., Kalden, Joachim R., Schett, Georg, Rovere-Querini, Patrizia, Herrmann, Martin, Voll, Reinhard E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605236/
https://ncbi.nlm.nih.gov/pubmed/19064698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081165
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