Dendritic cells in the thymus contribute to T-regulatory cell induction

Central tolerance is established through negative selection of self-reactive thymocytes and the induction of T-regulatory cells (T(R)s). The role of thymic dendritic cells (TDCs) in these processes has not been clearly determined. In this study, we demonstrate that in vivo, TDCs not only play a role...

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Détails bibliographiques
Auteurs principaux: Proietto, Anna I., van Dommelen, Serani, Zhou, Penghui, Rizzitelli, Alexandra, D'Amico, Angela, Steptoe, Raymond J., Naik, Shalin H., Lahoud, Mireille H., Liu, Yang, Zheng, Pan, Shortman, Ken, Wu, Li
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604962/
https://ncbi.nlm.nih.gov/pubmed/19073916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810268105
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