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Mu/Kappa Opioid Interactions in Rhesus Monkeys: Implications for Analgesia and Abuse Liability

Mu opioid receptor agonists are clinically valuable as analgesics; however, their use is limited by high abuse liability. Kappa opioid agonists also produce antinociception, but they do not produce mu agonist-like abuse-related effects, suggesting that they may enhance the antinociceptive effects an...

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Main Authors: Negus, S. Stevens, Katrina Schrode, KA, Stevenson, Glenn W.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604909/
https://ncbi.nlm.nih.gov/pubmed/18837635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0013088
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