Physiological and pathological aspects of Aβ in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators

Many studies have highlighted the pathological involvement of iron accumulation and iron-related oxidative stress (OS) in Alzheimer's disease (AD). Iron was further demonstrated to modulate expression of the Alzheimer's amyloid precursor holo-protein (APP) by a mechanism similar to that of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Avramovich-Tirosh, Yael, Amit, Tamar, Bar-Am, Orit, Weinreb, Orly, Youdim, Moussa BH
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2008
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604902/
https://ncbi.nlm.nih.gov/pubmed/19090990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-S2-S2
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