Epibatidine Application In Vitro Blocks Retinal Waves Without Silencing All Retinal Ganglion Cell Action Potentials in Developing Retina of the Mouse and Ferret

Epibatidine (EPI), a potent cholinergic agonist, disrupts acetylcholine-dependent spontaneous retinal activity. Early patch-clamp recordings in juvenile ferrets suggested that EPI blocks all retinal ganglion cell (RGC) action potentials when applied to the retina. In contrast, recent experiments on...

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Hauptverfasser: Sun, Chao, Speer, Colenso M., Wang, Guo-Yong, Chapman, Barbara, Chalupa, Leo M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2008
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604840/
https://ncbi.nlm.nih.gov/pubmed/18922954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.90303.2008
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