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The Genetic Basis of HIV-1 Resistance to Reverse Transcriptase and Protease Inhibitors

HIV-1 drug resistance is caused by mutations in the reverse transcriptase (RT) and protease enzymes, the molecular targets of antiretroviral therapy. At the beginning of the year 2000, two expert panels recommended that HIV-1 RT and protease susceptibility testing be used to help select antiretrovir...

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Bibliografski detalji
Glavni autori: Shafer, Robert W., Kantor, Rami, Gonzales, Matthew J.
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604813/
https://ncbi.nlm.nih.gov/pubmed/19096725
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