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Accentuated Osteoclastic Response to Parathyroid Hormone Undermines Bone Mass Acquisition in Osteonectin-null Mice

Matricellular proteins play a unique role in the skeleton as regulators of bone remodeling, and the matricellular protein osteonectin (SPARC, BM-40) is the most abundant non-collagenous protein in bone. In the absence of osteonectin, mice develop progressive low turnover osteopenia, particularly aff...

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Detalhes bibliográficos
Main Authors: do Reis, Luciene Machado, Kessler, Catherine B., Adams, Douglas J., Lorenzo, Joseph, Jorgetti, Vanda, Delany, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604811/
https://ncbi.nlm.nih.gov/pubmed/18499553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.03.024
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