Interaction of pneumococcal phase variation and middle ear pressure/gas composition: An in vitro model of simulated otitis media (Ms. Ref. No.: YMPAT-D-08-00046)

Streptococcus pneumoniae, a leading cause of otitis media (OM), undergoes spontaneous intra-strain variations in colony morphology. Transparent (T) variant is more efficient in colonizing the nasopharynx while the opaque (O) variant exhibits greater virulence during systemic infections. We hypothesi...

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Bibliographische Detailangaben
Hauptverfasser: Li-Korotky, Ha-Sheng, Banks, Juliane M., Lo, Chia-Yee, Zeng, Fan-Rui, Stolz, Donna B., Swarts, J. Douglas, Doyle, William J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604118/
https://ncbi.nlm.nih.gov/pubmed/18619763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2008.05.004
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