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Virulence of iron transport mutants of Shigella flexneri and utilization of host iron compounds.

Mutants of Shigella flexneri defective in aerobactin-mediated iron transport were assayed for virulence in several model systems. A Tn5 insertion mutant was invasive in HeLa cells, lethal in the chicken embryo, and produced keratoconjunctivitis in the guinea pig, indicating little or no loss of abil...

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Main Authors: Lawlor, K M, Daskaleros, P A, Robinson, R E, Payne, S M
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC260379/
https://ncbi.nlm.nih.gov/pubmed/3028962
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