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Ichthyosis Update: Towards a Function-Driven Model of Pathogenesis of the Disorders of Cornification and the Role of Corneocyte Proteins in These Disorders

The genetic causes of most of the disorders of cornification have been uncovered. We now face the significant task of delineating how these mutations result in specific phenotypes. Because the permeability barrier resides in the extracellular lipid-enriched domains of the stratum corneum, it was ant...

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Detalhes bibliográficos
Main Authors: Schmuth, Matthias, Gruber, Robert, Elias, Peter M., Williams, Mary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603607/
https://ncbi.nlm.nih.gov/pubmed/18159904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yadr.2007.07.011
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