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Analgesic effects of N-acetylmuramyl-L-alanyl-D-isoglutamine in decreasing the acetic acid-induced abdominal-writhing response.

A new pharmacological action of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) is described. Pretreatment of male ddY mice with MDP, but not its biologically inactive analogs, significantly decreased the frequency of acetic acid-induced writhing movements more effectively than did acetylsalicylic aci...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Ogawa, T, Kotani, S
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1987
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3804449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.2.494-496.1987
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