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Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells

Recent studies have emphasized the importance of cellular microenvironment in modulating cell growth and signaling. In vitro, collagen matrices, Matrigel, and other synthetic support systems have been used to simulate in vivo microenvironments, and epithelial cells grown in these matrices manifest s...

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Detalhes bibliográficos
Main Authors: Serebriiskii, Ilya, Castelló-Cros, Remedios, Lamb, Acacia, Golemis, Erica A., Cukierman, Edna
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603546/
https://ncbi.nlm.nih.gov/pubmed/18411046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2008.02.008
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