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Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells

Recent studies have emphasized the importance of cellular microenvironment in modulating cell growth and signaling. In vitro, collagen matrices, Matrigel, and other synthetic support systems have been used to simulate in vivo microenvironments, and epithelial cells grown in these matrices manifest s...

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Autori principali: Serebriiskii, Ilya, Castelló-Cros, Remedios, Lamb, Acacia, Golemis, Erica A., Cukierman, Edna
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603546/
https://ncbi.nlm.nih.gov/pubmed/18411046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2008.02.008
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