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PPARγ agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms

Peroxisome proliferator-activated receptor (PPAR)-γ is a ligand-activated transcription factor of nuclear hormone receptor superfamily. Thiazolidinedione rosiglitazone is a potent agonist of PPARγ which was shown to induce neuroprotection in animal models of focal ischemia and spinal cord injury. We...

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Detalhes bibliográficos
Main Authors: Yi, Jae-Hyuk, Park, Seung-Won, Brooks, Nathaniel, Lang, Bradley T., Vemuganti, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603294/
https://ncbi.nlm.nih.gov/pubmed/18948087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.09.074
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