Positive Selection Results in Frequent Reversible Amino Acid Replacements in the G Protein Gene of Human Respiratory Syncytial Virus

Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter. Multiple lineages of the HRSVA and HRSVB serotypes co-circulate within a single outbreak an...

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Auteurs principaux: Botosso, Viviane F., Zanotto, Paolo M. de A., Ueda, Mirthes, Arruda, Eurico, Gilio, Alfredo E., Vieira, Sandra E., Stewien, Klaus E., Peret, Teresa C. T., Jamal, Leda F., Pardini, Maria I. de M. C., Pinho, João R. R., Massad, Eduardo, Sant'Anna, Osvaldo A., Holmes, Eddie C., Durigon, Edison L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603285/
https://ncbi.nlm.nih.gov/pubmed/19119418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000254
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