Safety and Immunogenicity of a Recombinant Plasmodium falciparum AMA1 Malaria Vaccine Adjuvanted with Alhydrogel™, Montanide ISA 720 or AS02

BACKGROUND: Plasmodium falciparum Apical Membrane Antigen 1 (PfAMA1) is a candidate vaccine antigen expressed by merozoites and sporozoites. It plays a key role in red blood cell and hepatocyte invasion that can be blocked by antibodies. METHODOLOGY/PRINCIPAL FINDINGS: We assessed the safety and imm...

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Autors principals: Roestenberg, Meta, Remarque, Ed, de Jonge, Erik, Hermsen, Rob, Blythman, Hildur, Leroy, Odile, Imoukhuede, Egeruan, Jepsen, Soren, Ofori-Anyinam, Opokua, Faber, Bart, Kocken, Clemens H. M., Arnold, Miranda, Walraven, Vanessa, Teelen, Karina, Roeffen, Will, de Mast, Quirijn, Ballou, W. Ripley, Cohen, Joe, Dubois, Marie Claude, Ascarateil, Stéphane, van der Ven, Andre, Thomas, Alan, Sauerwein, Robert
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602972/
https://ncbi.nlm.nih.gov/pubmed/19093004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003960
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