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Safety and Immunogenicity of a Recombinant Plasmodium falciparum AMA1 Malaria Vaccine Adjuvanted with Alhydrogel™, Montanide ISA 720 or AS02
BACKGROUND: Plasmodium falciparum Apical Membrane Antigen 1 (PfAMA1) is a candidate vaccine antigen expressed by merozoites and sporozoites. It plays a key role in red blood cell and hepatocyte invasion that can be blocked by antibodies. METHODOLOGY/PRINCIPAL FINDINGS: We assessed the safety and imm...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Public Library of Science
2008
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602972/ https://ncbi.nlm.nih.gov/pubmed/19093004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003960 |
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