Specific Targeting of Pro-Death NMDA Receptor Signals with Differing Reliance on the NR2B PDZ Ligand

NMDA receptors (NMDARs) mediate ischemic brain damage, for which interactions between the C termini of NR2 subunits and PDZ domain proteins within the NMDAR signaling complex (NSC) are emerging therapeutic targets. However, expression of NMDARs in a non-neuronal context, lacking many NSC components,...

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Main Authors: Soriano, Francesc X., Martel, Marc-Andre, Papadia, Sofia, Vaslin, Anne, Baxter, Paul, Rickman, Colin, Forder, Joan, Tymianski, Michael, Duncan, Rory, Aarts, Michelle, Clarke, Peter G. H., Wyllie, David J. A., Hardingham, Giles E.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2008
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602846/
https://ncbi.nlm.nih.gov/pubmed/18923045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1207-08.2008
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