Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1

Rotavirus RNA-dependent RNA polymerase, VP1, catalyzes RNA synthesis within a subviral particle. This activity depends on core shell protein VP2. A conserved sequence at the 3′ end of plus-strand RNA templates is important for polymerase association and genome replication. We have determined the str...

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Autores principales: Lu, Xiaohui, McDonald, Sarah M., Tortorici, M. Alejandra, Tao, Yizhi Jane, Carpio, Rodrigo Vasquez-Del, Nibert, Max L., Patton, John T., Harrison, Stephen C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602806/
https://ncbi.nlm.nih.gov/pubmed/19000820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.09.006
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