Depurination within the intergenic region of Brome mosaic virus RNA3 inhibits viral replication in vitro and in vivo

Pokeweed antiviral protein (PAP) is a glycosidase of plant origin that has been shown to depurinate some viral RNAs in vitro. We have demonstrated previously that treatment of Brome mosaic virus (BMV) RNAs with PAP inhibited their translation in a cell-free system and decreased their accumulation in...

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Bibliographic Details
Main Authors: Karran, Rajita A., Hudak, Katalin A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602774/
https://ncbi.nlm.nih.gov/pubmed/19004869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn896
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