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The Communication Factor EDF and the Toxin–Antitoxin Module mazEF Determine the Mode of Action of Antibiotics

It was recently reported that the production of Reactive Oxygen Species (ROS) is a common mechanism of cell death induced by bactericidal antibiotics. Here we show that triggering the Escherichia coli chromosomal toxin–antitoxin system mazEF is an additional determinant in the mode of action of some...

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Bibliographic Details
Main Authors: Kolodkin-Gal, Ilana, Sat, Boaz, Keshet, Alex, Kulka, Hanna Engelberg-
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602726/
https://ncbi.nlm.nih.gov/pubmed/19090622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060319
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