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Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
Autophagy is responsible for nonspecific, bulk degradation of cytoplasmic components. Recent work has revealed also that there is specific, autophagic degradation of polyubiquitinated protein aggregates, whose buildup occurs during neurodegenerative disease. Here, we report that simple mono-ubiquiti...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602605/ https://ncbi.nlm.nih.gov/pubmed/19074260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810611105 |
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