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The Growth and Tumor Suppressors NORE1A and RASSF1A Are Targets for Calpain-Mediated Proteolysis
BACKGROUND: NORE1A and RASSF1A are growth and tumour suppressors inactivated in a variety of cancers. Methylation of NORE1A and RASSF1A promoters is the predominant mechanism for downregulation of these proteins; however, other mechanisms are likely to exist. METHODOLOGY/PRINCIPAL FINDINGS: Here we...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602596/ https://ncbi.nlm.nih.gov/pubmed/19098985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003997 |
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