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Depletion of Intestinal Phosphate following Surgical Injury Activates the Virulence of P. aeruginosa causing Lethal Gut-Derived Sepsis
BACKGROUND: Here we explored the possibility that the opportunistic pathogen, Pseudomonas aeruginosa (P.a) senses low phosphate (Pi) as a signal of host injury and shifts to a lethal phenotype. METHODS: Virulence expression in P. aeruginosa was examined in vitro under low phosphate conditions by ass...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2601706/ https://ncbi.nlm.nih.gov/pubmed/18656625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2008.03.045 |
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