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Cholecystokinin Regulates Expression of Y2 Receptors in Vagal Afferent Neurons Serving the Stomach

The intestinal hormones CCK and PYY3–36 inhibit gastric emptying and food intake via vagal afferent neurons. Here we report that CCK regulates the expression of Y2R, at which PYY3–36 acts. In nodose ganglia from rats fasted up to 48 h, there was a fivefold decrease of Y2R mRNA compared with rats fed...

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Autores principales: Burdyga, Galina, de Lartigue, Guillaume, Raybould, Helen E., Morris, Richard, Dimaline, Rod, Varro, Andrea, Thompson, David G., Dockray, Graham J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601630/
https://ncbi.nlm.nih.gov/pubmed/18987194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2493-08.2008
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