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Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy

Modified lipoproteins are immunogenic and play a key pathogenic role in vascular disease. Antibodies to oxidized LDL (oxLDL) are mostly of the proinflammatory IgG(1) and IgG(3) isotypes. We measured IgG and IgM oxLDL antibodies in immune complexes (IC) isolated from 36 patients with type 1 diabetes...

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Detalhes bibliográficos
Main Authors: Virella, Gabriel, Carter, Rickey E., Saad, Antonio, Crosswell, Edward G., Game, B. Andrew, Lopes-Virella, Maria F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601558/
https://ncbi.nlm.nih.gov/pubmed/18533284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.02.005
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