Retinal Ganglion Cell Apoptosis in Glaucoma Is Related to Intraocular Pressure and IOP-Induced Effects on Extracellular Matrix

PURPOSE: To investigate the effect of IOP on retinal ganglion cell (RGC) apoptosis and correlate the effects with IOP-induced changes in extracellular matrix (ECM) in the retina and optic nerve head (ONH) in glaucomatous rat eyes. METHODS: Thirty-seven Dark Agouti rats had elevated IOP induced in th...

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Main Authors: Guo, Li, Moss, Stephen E., Alexander, Robert A., Ali, Robin R., Fitzke, Frederick W., Cordeiro, M. Francesca
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601028/
https://ncbi.nlm.nih.gov/pubmed/15623771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.04-0832
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