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Ultraconserved Elements: Analyses of Dosage Sensitivity, Motifs and Boundaries

Ultraconserved elements (UCEs) are sequences that are identical between reference genomes of distantly related species. As they are under negative selection and enriched near or in specific classes of genes, one explanation for their ultraconservation may be their involvement in important functions....

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Detalhes bibliográficos
Main Authors: Chiang, Charleston W. K., Derti, Adnan, Schwartz, Daniel, Chou, Michael F., Hirschhorn, Joel N., Wu, C.-ting
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600958/
https://ncbi.nlm.nih.gov/pubmed/18957701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.096537
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