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Sexual Back Talk With Evolutionary Implications: Stimulation of the Drosophila Sex-Determination Gene Sex-lethal by Its Target transformer

We describe a surprising new regulatory relationship between two key genes of the Drosophila sex-determination gene hierarchy, Sex-lethal (Sxl) and transformer (tra). A positive autoregulatory feedback loop for Sxl was known to maintain somatic cell female identity by producing SXL-F protein to cont...

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Autori principali: Siera, Scott G., Cline, Thomas W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600935/
https://ncbi.nlm.nih.gov/pubmed/18845845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.093898
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