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Microinjection of muscimol into the dorsomedial hypothalamus suppresses MDMA-evoked sympathetic and behavioral responses

When given systemically to rats and humans, the drug of abuse 3–4 methylenedioxymethamphetamine (ecstasy, MDMA) elicits hyperthermia, hyperactivity, tachycardia, and hypertension. Chemically stimulating the dorsomedial hypothalamus (DMH), a brain region known to be involved in thermoregulation and i...

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Detalhes bibliográficos
Main Authors: Rusyniak, Daniel E., Zaretskaia, Maria V., Zaretsky, Dmitry V., DiMicco, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600867/
https://ncbi.nlm.nih.gov/pubmed/18586013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.06.011
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