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EVALUATION OF STRATEGIES FOR THE SYNTHESIS OF THE GUANIDINE HEMIAMINAL PORTION OF PALAU’AMINE

Potential methods for the generation of the guanidine hemiaminal functionality of palau’mine (1) from a spirocyclic thiohydantoin precursor are examined using a spirobicyclic model system, culminating in the identification of an efficient means of effecting this transformation.

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Detalhes bibliográficos
Main Authors: Lanman, Brian A., Overman, Larry E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600862/
https://ncbi.nlm.nih.gov/pubmed/19079749
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