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Peak intensity prediction in MALDI-TOF mass spectrometry: A machine learning study to support quantitative proteomics

BACKGROUND: Mass spectrometry is a key technique in proteomics and can be used to analyze complex samples quickly. One key problem with the mass spectrometric analysis of peptides and proteins, however, is the fact that absolute quantification is severely hampered by the unclear relationship between...

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Detalhes bibliográficos
Main Authors: Timm, Wiebke, Scherbart, Alexandra, Böcker, Sebastian, Kohlbacher, Oliver, Nattkemper, Tim W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600826/
https://ncbi.nlm.nih.gov/pubmed/18937839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-443
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