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QM/MM Minimum Free Energy Path: Methodology and Application to Triosephosphate Isomerase

Structural and energetic changes are two important characteristic properties of a chemical reaction process. In the condensed phase, studying these two properties is very challenging because of the great computational cost associated with the quantum mechanical calculations and phase space sampling....

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Bibliografiske detaljer
Main Authors: Hu, Hao, Lu, Zhenyu, Yang, Weitao
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600730/
https://ncbi.nlm.nih.gov/pubmed/19079734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct600240y
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