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A pharmacological comparison of the cloned frog and human mu opioid receptors reveals differences in opioid affinity and function

This study presents a direct comparison of the ligand binding and signaling profiles of a mammalian and non-mammalian mu opioid receptor. Opioid ligand binding and agonist potencies were determined for an amphibian (Rana pipiens) mu opioid receptor (rpMOR) and the human mu opioid receptor (hMOR) in...

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Detalhes bibliográficos
Main Authors: Brasel, Chris M., Sawyer, Gregory W., Stevens, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600596/
https://ncbi.nlm.nih.gov/pubmed/18930720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.09.043
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