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Beta hydroxylation of the aspartyl residue in the phytotoxin syringomycin E: characterization of two candidate hydroxylases AspH and SyrP in Pseudomonas syringae

The pseudomonal phytotoxin syringomycin E, and related nonribosomal peptides, contain an L-threo-β-hydroxy-aspartyl residue at the eighth position of the lipodepsipeptide backbone as part of a conserved nonproteinogenic tripeptide motif. Informatic analysis of the P. syringae genome suggests only on...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Singh, Gitanjali M., Fortin, Pascal, Koglin, Alexander, Walsh, Christopher T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600472/
https://ncbi.nlm.nih.gov/pubmed/18826255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801322z
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