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Polyamine Sharing between Tubulin Dimers Favours Microtubule Nucleation and Elongation via Facilitated Diffusion

We suggest for the first time that the action of multivalent cations on microtubule dynamics can result from facilitated diffusion of GTP-tubulin to the microtubule ends. Facilitated diffusion can promote microtubule assembly, because, upon encountering a growing nucleus or the microtubule wall, ran...

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Bibliografiske detaljer
Main Authors: Mechulam, Alain, Chernov, Konstantin G., Mucher, Elodie, Hamon, Loic, Curmi, Patrick A., Pastré, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599886/
https://ncbi.nlm.nih.gov/pubmed/19119409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000255
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