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Polyamine Sharing between Tubulin Dimers Favours Microtubule Nucleation and Elongation via Facilitated Diffusion

We suggest for the first time that the action of multivalent cations on microtubule dynamics can result from facilitated diffusion of GTP-tubulin to the microtubule ends. Facilitated diffusion can promote microtubule assembly, because, upon encountering a growing nucleus or the microtubule wall, ran...

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Detalhes bibliográficos
Main Authors: Mechulam, Alain, Chernov, Konstantin G., Mucher, Elodie, Hamon, Loic, Curmi, Patrick A., Pastré, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599886/
https://ncbi.nlm.nih.gov/pubmed/19119409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000255
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