Reduced Basal ATP Synthetic Flux of Skeletal Muscle in Patients with Previous Acromegaly

BACKGROUND: Impaired mitochondrial function and ectopic lipid deposition in skeletal muscle and liver have been linked to decreased insulin sensitivity. As growth hormone (GH) excess can reduce insulin sensitivity, we examined the impact of previous acromegaly (AM) on glucose metabolism, lipid stora...

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Hauptverfasser: Szendroedi, Julia, Zwettler, Elisabeth, Schmid, Albrecht Ingo, Chmelik, Marek, Pacini, Giovanni, Kacerovsky, Gertrud, Smekal, Gerhard, Nowotny, Peter, Wagner, Oswald, Schnack, Christoph, Schernthaner, Guntram, Klaushofer, Klaus, Roden, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599885/
https://ncbi.nlm.nih.gov/pubmed/19093000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003958
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